Drug interactions
Chlorpromazine + Methyl aminolevulinate
Severity: Moderate
Chlorpromazine and Methyl aminolevulinate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chlorpromazine is a phototoxic drug and methyl aminolevulinate is a topical photosensitizer used with light therapy. Together they may increase the skin's reaction to light, with more intense erythema or burning.
What this interaction means in plain words
Chlorpromazine and Methyl aminolevulinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive photosensitization of the skin.
What to do
Counsel on strict sun protection and watch the treated area for exaggerated phototoxic reactions. Consider delaying photodynamic therapy if a safe interruption of chlorpromazine is possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chlorpromazine
- Chlorpromazine + Dofetilide Contraindicated
- Chlorpromazine + Dronedarone Contraindicated
- Chlorpromazine + Droperidol Contraindicated
- Chlorpromazine + Ibutilide Contraindicated
- Chlorpromazine + Metrizamide Contraindicated
- Chlorpromazine + Panobinostat Contraindicated
Frequently asked questions
Can I take Chlorpromazine with Methyl aminolevulinate?
MediHelp rates the interaction as moderate. Chlorpromazine and Methyl aminolevulinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlorpromazine is a phototoxic drug and methyl aminolevulinate is a topical photosensitizer used with light therapy. Together they may increase the skin's reaction to light, with more intense erythema or burning.
How serious is the interaction between Chlorpromazine and Methyl aminolevulinate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on strict sun protection and watch the treated area for exaggerated phototoxic reactions. Consider delaying photodynamic therapy if a safe interruption of chlorpromazine is possible.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Droperidol. The full list is on the Chlorpromazine page.
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