Drug interactions
Chlorthalidone + Mometasone
Severity: Minor
Chlorthalidone and Mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both corticosteroids and thiazide-like diuretics can lower serum potassium. With inhaled mometasone systemic exposure is low, so the effect is usually small.
What this interaction means in plain words
Chlorthalidone and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chlorthalidone belongs to Cardiovascular; Mometasone belongs to Respiratory.
Why it happens
Additive renal potassium loss; systemic corticosteroid exposure from inhalation is low.
What to do
Check potassium periodically in patients with other hypokalemia risks or on high steroid doses. No routine action is needed otherwise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mometasone
- Mometasone + Ritonavir Major
- Atazanavir + Mometasone Moderate
- Clarithromycin + Mometasone Moderate
- Cobicistat + Mometasone Moderate
- Darunavir + Mometasone Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Mometasone Moderate
Other interactions of Chlorthalidone
Frequently asked questions
Can I take Chlorthalidone with Mometasone?
MediHelp rates the interaction as minor. Chlorthalidone and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both corticosteroids and thiazide-like diuretics can lower serum potassium. With inhaled mometasone systemic exposure is low, so the effect is usually small.
How serious is the interaction between Chlorthalidone and Mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium periodically in patients with other hypokalemia risks or on high steroid doses. No routine action is needed otherwise.
What other medicines interact with Mometasone?
MediHelp also lists interactions of Mometasone with, for example, Ritonavir, Atazanavir, Clarithromycin. The full list is on the Mometasone page.
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