Drug interactions
Cidofovir + Ublituximab
Severity: Moderate
Cidofovir and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and increases infection risk, which may be relevant in patients treated with cidofovir for viral infections. Cidofovir is not made less effective, but combined immune compromise may worsen outcomes.
What this interaction means in plain words
Cidofovir and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cidofovir belongs to Anti Virals; Ublituximab belongs to Miscellaneous.
Why it happens
Pharmacodynamic: immunosuppression from B-cell depletion in patients needing antiviral therapy; no pharmacokinetic interaction.
What to do
Monitor for infection and clinical response to antiviral therapy, and reassess the need for ublituximab during active serious infection.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cidofovir
- Amikacin + Cidofovir Contraindicated
- Amphotericin b deoxycholate + Cidofovir Contraindicated
- Amphotericin b + Cidofovir Contraindicated
- Bacitracin + Cidofovir Contraindicated
- Capreomycin + Cidofovir Contraindicated
- Cephaloridine + Cidofovir Contraindicated
Other interactions of Ublituximab
Frequently asked questions
Can I take Cidofovir with Ublituximab?
MediHelp rates the interaction as moderate. Cidofovir and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ublituximab depletes B cells and increases infection risk, which may be relevant in patients treated with cidofovir for viral infections. Cidofovir is not made less effective, but combined immune compromise may worsen outcomes.
How serious is the interaction between Cidofovir and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for infection and clinical response to antiviral therapy, and reassess the need for ublituximab during active serious infection.
What other medicines interact with Cidofovir?
MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.
Full monographs, dosing and an interaction checker in the MediHelp app
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