Drug interactions
Cilostazol + Iloperidone
Severity: Minor
Cilostazol and Iloperidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloperidone is a weak time-dependent CYP3A inhibitor and may slightly raise cilostazol levels. Both drugs can affect cardiac conduction or heart rate, so tachycardia may be of concern.
What this interaction means in plain words
Cilostazol and Iloperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cilostazol belongs to Cardiovascular; Iloperidone belongs to Central Nervous System.
Why it happens
Weak, time-dependent CYP3A4 inhibition by iloperidone reduces cilostazol clearance.
What to do
No routine dose change; monitor heart rate and ECG if clinically indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cilostazol
Other interactions of Iloperidone
- Iloperidone + Thioridazine Contraindicated
- Alfuzosin + Iloperidone Major
- Amiodarone + Iloperidone Major
- Amisulpride + Iloperidone Major
- Amitriptyline + Iloperidone Major
- Anagrelide + Iloperidone Major
Frequently asked questions
Can I take Cilostazol with Iloperidone?
MediHelp rates the interaction as minor. Cilostazol and Iloperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iloperidone is a weak time-dependent CYP3A inhibitor and may slightly raise cilostazol levels. Both drugs can affect cardiac conduction or heart rate, so tachycardia may be of concern.
How serious is the interaction between Cilostazol and Iloperidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change; monitor heart rate and ECG if clinically indicated.
What other medicines interact with Cilostazol?
MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.
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