Drug interactions
Ciprofloxacin + Saxagliptin
Severity: Minor
Ciprofloxacin and Saxagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoroquinolones are associated with dysglycemia, and this may be additive in patients on glucose-lowering drugs. Saxagliptin alone has low hypoglycemia risk, so the clinical effect is probably modest.
What this interaction means in plain words
Ciprofloxacin and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ciprofloxacin belongs to Anti Bacterial; Saxagliptin belongs to Endocrine.
Why it happens
Fluoroquinolone effects on insulin secretion and glucose handling; the mechanism is not clearly established.
What to do
Advise patients to monitor blood glucose during ciprofloxacin treatment. Review therapy if marked glucose changes occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Frequently asked questions
Can I take Ciprofloxacin with Saxagliptin?
MediHelp rates the interaction as minor. Ciprofloxacin and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluoroquinolones are associated with dysglycemia, and this may be additive in patients on glucose-lowering drugs. Saxagliptin alone has low hypoglycemia risk, so the clinical effect is probably modest.
How serious is the interaction between Ciprofloxacin and Saxagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to monitor blood glucose during ciprofloxacin treatment. Review therapy if marked glucose changes occur.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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