Drug interactions
Clarithromycin + Formoterol-mometasone
Severity: Moderate
Clarithromycin and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Clarithromycin prolongs the QT interval and can cause torsades de pointes. Formoterol may add to this through hypokalemia and tachycardia, and clarithromycin may modestly raise formoterol exposure.
What this interaction means in plain words
Clarithromycin and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Clarithromycin belongs to Anti Bacterial; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT prolongation with beta-2 agonist hypokalemia.
What to do
Consider an alternative antibiotic such as azithromycin if QT risk is high; otherwise monitor ECG and potassium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Clarithromycin
- Astemizole + Clarithromycin Contraindicated
- Avanafil + Clarithromycin Contraindicated
- Cisapride + Clarithromycin Contraindicated
- Clarithromycin + Colchicine Contraindicated
- Clarithromycin + Conivaptan Contraindicated
- Clarithromycin + Dihydroergotamine Contraindicated
Frequently asked questions
Can I take Clarithromycin with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Clarithromycin and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Clarithromycin prolongs the QT interval and can cause torsades de pointes. Formoterol may add to this through hypokalemia and tachycardia, and clarithromycin may modestly raise formoterol exposure.
How serious is the interaction between Clarithromycin and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider an alternative antibiotic such as azithromycin if QT risk is high; otherwise monitor ECG and potassium.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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