Drug interactions
clarithromycin + ivabradine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↑ ivabradine → bradycardia/QT; contraindicated.
Mechanism of action
Strong CYP3A4 inhibition.
Clinical management
Contraindicated.
Drug reference
References
Frequently asked questions
Can I take clarithromycin with ivabradine?
The interaction is rated: Contraindicated. ↑ ivabradine → bradycardia/QT; contraindicated.
How serious is the interaction between clarithromycin and ivabradine?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between clarithromycin and ivabradine managed?
Contraindicated.
Why do clarithromycin and ivabradine interact?
Strong CYP3A4 inhibition.
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