Drug interactions
Clindamycin + Nitazoxanide
Severity: Minor
Clindamycin and Nitazoxanide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tizoxanide, the active metabolite of nitazoxanide, is highly protein bound, but displacement interactions of this kind are rarely clinically significant. No meaningful effect on clindamycin is documented.
What this interaction means in plain words
Clindamycin and Nitazoxanide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clindamycin belongs to Anti Bacterial; Nitazoxanide belongs to Anti Bacterial.
Why it happens
Theoretical competition for plasma protein binding sites.
What to do
No specific intervention is needed; monitor clinical response and tolerability.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clindamycin
Other interactions of Nitazoxanide
Frequently asked questions
Can I take Clindamycin with Nitazoxanide?
MediHelp rates the interaction as minor. Clindamycin and Nitazoxanide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tizoxanide, the active metabolite of nitazoxanide, is highly protein bound, but displacement interactions of this kind are rarely clinically significant. No meaningful effect on clindamycin is documented.
How serious is the interaction between Clindamycin and Nitazoxanide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific intervention is needed; monitor clinical response and tolerability.
What other medicines interact with Clindamycin?
MediHelp also lists interactions of Clindamycin with, for example, Atracurium, Cisatracurium, Microbiota. The full list is on the Clindamycin page.
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