Drug interactions
Clobazam + Tamsulosin
Severity: Minor
Clobazam and Tamsulosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Clobazam is a weak CYP2D6 inhibitor and may modestly increase tamsulosin exposure. This could increase dizziness or hypotension, though the effect is generally small.
What this interaction means in plain words
Clobazam and Tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clobazam belongs to Central Nervous System; Tamsulosin belongs to Genitourinary.
Why it happens
Weak inhibition of CYP2D6 reducing tamsulosin clearance.
What to do
No dose change is usually needed. Monitor for orthostatic symptoms when starting or increasing clobazam.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tamsulosin
- Alfuzosin + Tamsulosin Major
- Avanafil + Tamsulosin Major
- Ceritinib + Tamsulosin Major
- Clarithromycin + Tamsulosin Major
- Cobicistat + Tamsulosin Major
- Doxazosin + Tamsulosin Major
Other interactions of Clobazam
- Amobarbital + Clobazam Major
- Buprenorphine + Clobazam Major
- Butorphanol + Clobazam Major
- Carisoprodol + Clobazam Major
- Chloral hydrate + Clobazam Major
- Clobazam + Clozapine Major
Frequently asked questions
Can I take Clobazam with Tamsulosin?
MediHelp rates the interaction as minor. Clobazam and Tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Clobazam is a weak CYP2D6 inhibitor and may modestly increase tamsulosin exposure. This could increase dizziness or hypotension, though the effect is generally small.
How serious is the interaction between Clobazam and Tamsulosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed. Monitor for orthostatic symptoms when starting or increasing clobazam.
What other medicines interact with Tamsulosin?
MediHelp also lists interactions of Tamsulosin with, for example, Alfuzosin, Avanafil, Ceritinib. The full list is on the Tamsulosin page.
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