Drug interactions
Clomipramine + Formoterol-mometasone
Severity: Moderate
Clomipramine and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Clomipramine can prolong QT and may potentiate the cardiovascular effects of beta-agonists. Formoterol hypokalemia further raises arrhythmia risk.
What this interaction means in plain words
Clomipramine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Clomipramine belongs to Central Nervous System; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT prolongation and adrenergic potentiation from reuptake inhibition.
What to do
Monitor heart rate, ECG and potassium, particularly with high doses or cardiac disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Clomipramine
- Arsenic trioxide + Clomipramine Contraindicated
- Clomipramine + Dofetilide Contraindicated
- Clomipramine + Droperidol Contraindicated
- Clomipramine + Isocarboxazid Contraindicated
- Clomipramine + Methylene blue Contraindicated
- Clomipramine + Pentamidine Contraindicated
Frequently asked questions
Can I take Clomipramine with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Clomipramine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Clomipramine can prolong QT and may potentiate the cardiovascular effects of beta-agonists. Formoterol hypokalemia further raises arrhythmia risk.
How serious is the interaction between Clomipramine and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, ECG and potassium, particularly with high doses or cardiac disease.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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