Drug interactions
Clonidine + Vildagliptin
Severity: Minor
Clonidine and Vildagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vildagliptin alone has low hypoglycemia risk, so symptom masking by clonidine is of little practical relevance.
What this interaction means in plain words
Clonidine and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clonidine belongs to Cardiovascular; Vildagliptin belongs to Endocrine.
Why it happens
Theoretical blunting of adrenergic hypoglycemia symptoms by central alpha-2 agonism.
What to do
No specific action needed. Monitor glucose if combined with insulin or sulfonylureas.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clonidine
- Acebutolol + Clonidine Major
- Amifostine + Clonidine Major
- Amiodarone + Clonidine Major
- Amoxapine + Clonidine Major
- Atenolol-chlorthalidone + Clonidine Major
- Atenolol + Clonidine Major
Other interactions of Vildagliptin
- Ciprofloxacin + Vildagliptin Moderate
- Deflazacort + Vildagliptin Moderate
- Dexamethasone + Vildagliptin Moderate
- Gemifloxacin + Vildagliptin Moderate
- Glimepiride + Vildagliptin Moderate
- Hydrochlorothiazide-lisinopril + Vildagliptin Moderate
Frequently asked questions
Can I take Clonidine with Vildagliptin?
MediHelp rates the interaction as minor. Clonidine and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vildagliptin alone has low hypoglycemia risk, so symptom masking by clonidine is of little practical relevance.
How serious is the interaction between Clonidine and Vildagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action needed. Monitor glucose if combined with insulin or sulfonylureas.
What other medicines interact with Clonidine?
MediHelp also lists interactions of Clonidine with, for example, Acebutolol, Amifostine, Amiodarone. The full list is on the Clonidine page.
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