Drug interactions
Clopidogrel + Nilutamide
Severity: Minor
Clopidogrel and Nilutamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nilutamide is reported to inhibit CYP enzymes and could reduce activation of clopidogrel. The clinical significance is not established and the evidence is largely theoretical.
What this interaction means in plain words
Clopidogrel and Nilutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clopidogrel belongs to Cardiovascular; Nilutamide belongs to Endocrine.
Why it happens
Possible CYP inhibition reducing hepatic conversion of clopidogrel to its active metabolite; not well characterized.
What to do
No routine change is needed; stay alert for reduced antiplatelet response in high thrombotic risk patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clopidogrel
Other interactions of Nilutamide
Frequently asked questions
Can I take Clopidogrel with Nilutamide?
MediHelp rates the interaction as minor. Clopidogrel and Nilutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nilutamide is reported to inhibit CYP enzymes and could reduce activation of clopidogrel. The clinical significance is not established and the evidence is largely theoretical.
How serious is the interaction between Clopidogrel and Nilutamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; stay alert for reduced antiplatelet response in high thrombotic risk patients.
What other medicines interact with Clopidogrel?
MediHelp also lists interactions of Clopidogrel with, for example, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Abrocitinib, Acetylsalicylic acid. The full list is on the Clopidogrel page.
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