Drug interactions
Conivaptan + Dutasteride
Severity: Minor
Conivaptan and Dutasteride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Conivaptan is a CYP3A4 inhibitor and could raise dutasteride concentrations. Conivaptan is given only short-term in hospital, so the effect is likely trivial.
What this interaction means in plain words
Conivaptan and Dutasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of CYP3A4-mediated dutasteride metabolism by conivaptan.
What to do
No dose adjustment is required. No specific monitoring is needed for the short course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dutasteride
- Dutasteride + Levoketoconazole Moderate
- Dutasteride + Nefazodone Moderate
- Dutasteride + Rifampin Moderate
- Dutasteride + St john's wort Moderate
- Amobarbital + Dutasteride Minor
- Aprepitant + Dutasteride Minor
Frequently asked questions
Can I take Conivaptan with Dutasteride?
MediHelp rates the interaction as minor. Conivaptan and Dutasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Conivaptan is a CYP3A4 inhibitor and could raise dutasteride concentrations. Conivaptan is given only short-term in hospital, so the effect is likely trivial.
How serious is the interaction between Conivaptan and Dutasteride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required. No specific monitoring is needed for the short course.
What other medicines interact with Dutasteride?
MediHelp also lists interactions of Dutasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Dutasteride page.
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