Drug interactions
Corticotropin + Testosterone
Severity: Moderate
Corticotropin and Testosterone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticotropin stimulates adrenal steroid release, and with androgens this can add to sodium and fluid retention and edema. Patients with heart, kidney or liver disease are most vulnerable.
What this interaction means in plain words
Corticotropin and Testosterone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Corticotropin belongs to Endocrine; Testosterone belongs to Endocrine.
Why it happens
Additive sodium and water retention from androgens and corticotropin-induced adrenal corticosteroid secretion.
What to do
Monitor weight, edema, blood pressure and electrolytes during combined use. Adjust therapy or add diuretics if fluid overload develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Testosterone
- Testosterone + Warfarin Major
- Androstenedione + Testosterone Moderate
- Betamethasone + Testosterone Moderate
- Carbamazepine + Testosterone Moderate
- Cortisone + Testosterone Moderate
- Cyclosporine + Testosterone Moderate
Other interactions of Corticotropin
Frequently asked questions
Can I take Corticotropin with Testosterone?
MediHelp rates the interaction as moderate. Corticotropin and Testosterone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticotropin stimulates adrenal steroid release, and with androgens this can add to sodium and fluid retention and edema. Patients with heart, kidney or liver disease are most vulnerable.
How serious is the interaction between Corticotropin and Testosterone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor weight, edema, blood pressure and electrolytes during combined use. Adjust therapy or add diuretics if fluid overload develops.
What other medicines interact with Testosterone?
MediHelp also lists interactions of Testosterone with, for example, Warfarin, Androstenedione, Betamethasone. The full list is on the Testosterone page.
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