Drug interactions
Cortisone + Dutasteride
Severity: Minor
Cortisone and Dutasteride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids have weak CYP3A4 induction potential, and a reduction in dutasteride exposure is theoretical. Clinical relevance is unlikely.
What this interaction means in plain words
Cortisone and Dutasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak CYP3A4 induction by cortisone; mechanism not well established.
What to do
No dose adjustment is necessary. Monitor therapeutic response to dutasteride as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dutasteride
- Dutasteride + Levoketoconazole Moderate
- Dutasteride + Nefazodone Moderate
- Dutasteride + Rifampin Moderate
- Dutasteride + St john's wort Moderate
- Amobarbital + Dutasteride Minor
- Aprepitant + Dutasteride Minor
Frequently asked questions
Can I take Cortisone with Dutasteride?
MediHelp rates the interaction as minor. Cortisone and Dutasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids have weak CYP3A4 induction potential, and a reduction in dutasteride exposure is theoretical. Clinical relevance is unlikely.
How serious is the interaction between Cortisone and Dutasteride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is necessary. Monitor therapeutic response to dutasteride as usual.
What other medicines interact with Dutasteride?
MediHelp also lists interactions of Dutasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Dutasteride page.
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