Drug interactions
Cyclizine + Ephedrine
Severity: Minor
Cyclizine and Ephedrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ephedrine is a sympathomimetic stimulant, whereas cyclizine is sedating. The stimulant effect may partly oppose drowsiness, but additive tachycardia is possible.
What this interaction means in plain words
Cyclizine and Ephedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclizine belongs to Respiratory; Ephedrine belongs to Cardiovascular.
Why it happens
Opposing CNS effects; possible additive effects on heart rate.
What to do
No routine adjustment is needed; monitor heart rate and blood pressure in patients with cardiovascular disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cyclizine
- Calcium / magnesium / potassium / sodium oxybates + Cyclizine Major
- Cyclizine + Henbane Major
- Cyclizine + Sodium oxybate Major
- Abobotulinumtoxina + Cyclizine Moderate
- Alfentanil + Cyclizine Moderate
- Alprazolam + Cyclizine Moderate
Other interactions of Ephedrine
- Ephedrine + Isocarboxazid Contraindicated
- Ephedrine + Phenelzine Contraindicated
- Ephedrine + Procarbazine Contraindicated
- Ephedrine + Rasagiline Contraindicated
- Ephedrine + Selegiline Contraindicated
- Ephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Cyclizine with Ephedrine?
MediHelp rates the interaction as minor. Cyclizine and Ephedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ephedrine is a sympathomimetic stimulant, whereas cyclizine is sedating. The stimulant effect may partly oppose drowsiness, but additive tachycardia is possible.
How serious is the interaction between Cyclizine and Ephedrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; monitor heart rate and blood pressure in patients with cardiovascular disease.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Henbane, Sodium oxybate. The full list is on the Cyclizine page.
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