Drug interactions
Cyclosporin + Glipizide
Severity: Minor
Cyclosporin and Glipizide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glycemic control may shift when cyclosporine is combined with a sulfonylurea, and a few reports suggest changes in cyclosporine exposure. The clinical effect is inconsistent and poorly characterized.
What this interaction means in plain words
Cyclosporin and Glipizide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Glipizide belongs to Endocrine.
Why it happens
The mechanism is not well established; possible effects on hepatic metabolism or glucose handling have been proposed.
What to do
Monitor blood glucose when starting or stopping cyclosporine and adjust the glipizide dose if needed. Check cyclosporine trough levels if clinical signs of altered exposure appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Other interactions of Glipizide
Frequently asked questions
Can I take Cyclosporin with Glipizide?
MediHelp rates the interaction as minor. Cyclosporin and Glipizide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glycemic control may shift when cyclosporine is combined with a sulfonylurea, and a few reports suggest changes in cyclosporine exposure. The clinical effect is inconsistent and poorly characterized.
How serious is the interaction between Cyclosporin and Glipizide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping cyclosporine and adjust the glipizide dose if needed. Check cyclosporine trough levels if clinical signs of altered exposure appear.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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