Drug interactions
Dalteparin + Vitamin e
Severity: Minor
Dalteparin and Vitamin e: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High-dose vitamin E has weak antiplatelet and vitamin K-antagonistic effects that may modestly increase bleeding tendency with anticoagulants. At usual dietary or supplement doses the effect with dalteparin is unlikely to be significant.
What this interaction means in plain words
Dalteparin and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dalteparin belongs to Cardiovascular; Vitamin e belongs to Gastrointestinal Tract.
Why it happens
High-dose vitamin E may inhibit platelet aggregation and interfere with vitamin K-dependent clotting, adding to anticoagulant effect.
What to do
Avoid high-dose vitamin E supplements during dalteparin therapy. Monitor for bleeding if they are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Other interactions of Vitamin e
- Betrixaban + Vitamin e Moderate
- Phenindione + Vitamin e Moderate
- Selumetinib + Vitamin e Moderate
- Vitamin e + Warfarin Moderate
- Alfalfa + Vitamin e Minor
- Antithrombin alfa + Vitamin e Minor
Frequently asked questions
Can I take Dalteparin with Vitamin e?
MediHelp rates the interaction as minor. Dalteparin and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High-dose vitamin E has weak antiplatelet and vitamin K-antagonistic effects that may modestly increase bleeding tendency with anticoagulants. At usual dietary or supplement doses the effect with dalteparin is unlikely to be significant.
How serious is the interaction between Dalteparin and Vitamin e?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid high-dose vitamin E supplements during dalteparin therapy. Monitor for bleeding if they are used.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
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