Drug interactions
Danazol + Fenofibric acid
Severity: Minor
Danazol and Fenofibric acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol inhibits CYP3A4, but this is a minor route for fenofibric acid, so a relevant exposure increase is unlikely. Both drugs can adversely affect lipids or the liver, which warrants general awareness.
What this interaction means in plain words
Danazol and Fenofibric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak CYP3A4 inhibition by danazol affecting a minor pathway of fenofibric acid.
What to do
No dose adjustment is needed; monitor lipid profile and liver enzymes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenofibric acid
- Atorvastatin + Fenofibric acid Moderate
- Chlorpropamide + Fenofibric acid Moderate
- Cholestyramine + Fenofibric acid Moderate
- Cholic acid + Fenofibric acid Moderate
- Colchicine + Fenofibric acid Moderate
- Colestipol + Fenofibric acid Moderate
Frequently asked questions
Can I take Danazol with Fenofibric acid?
MediHelp rates the interaction as minor. Danazol and Fenofibric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol inhibits CYP3A4, but this is a minor route for fenofibric acid, so a relevant exposure increase is unlikely. Both drugs can adversely affect lipids or the liver, which warrants general awareness.
How serious is the interaction between Danazol and Fenofibric acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor lipid profile and liver enzymes.
What other medicines interact with Fenofibric acid?
MediHelp also lists interactions of Fenofibric acid with, for example, Atorvastatin, Chlorpropamide, Cholestyramine. The full list is on the Fenofibric acid page.
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