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Drug interactions

Danazol + Montelukast

Severity: Minor

Danazol and Montelukast: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Danazol is a weak CYP3A4 inhibitor and may slightly increase montelukast exposure. The effect is expected to be small and rarely clinically relevant.

What this interaction means in plain words

Danazol and Montelukast have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Danazol inhibits CYP3A4, slightly reducing montelukast metabolism.

What to do

No dose adjustment is usually required. Monitor for adverse effects if both are used long-term.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Danazol with Montelukast?

MediHelp rates the interaction as minor. Danazol and Montelukast have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol is a weak CYP3A4 inhibitor and may slightly increase montelukast exposure. The effect is expected to be small and rarely clinically relevant.

How serious is the interaction between Danazol and Montelukast?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually required. Monitor for adverse effects if both are used long-term.

What other medicines interact with Montelukast?

MediHelp also lists interactions of Montelukast with, for example, Apalutamide, Carbamazepine, Deferasirox. The full list is on the Montelukast page.

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