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Drug interactions

Dapagliflozin-metformin + Mesterolone

Severity: Minor

Dapagliflozin-metformin and Mesterolone: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Androgens may improve insulin sensitivity and could enhance the glucose-lowering effect of antidiabetic drugs. The clinical impact is expected to be small.

What this interaction means in plain words

Dapagliflozin-metformin and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Dapagliflozin-metformin belongs to Endocrine; Mesterolone belongs to Endocrine.

Evidence level: Low

Why it happens

Androgens may alter insulin sensitivity and body composition; the mechanism for this interaction is not firmly established.

What to do

Monitor blood glucose when starting or stopping mesterolone and adjust antidiabetic doses if needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dapagliflozin-metformin with Mesterolone?

MediHelp rates the interaction as minor. Dapagliflozin-metformin and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgens may improve insulin sensitivity and could enhance the glucose-lowering effect of antidiabetic drugs. The clinical impact is expected to be small.

How serious is the interaction between Dapagliflozin-metformin and Mesterolone?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping mesterolone and adjust antidiabetic doses if needed.

What other medicines interact with Dapagliflozin-metformin?

MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.

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