Drug interactions
Dapagliflozin-metformin + Phentermine
Severity: Minor
Dapagliflozin-metformin and Phentermine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phentermine-related weight loss and reduced intake often lower antidiabetic requirements, so glucose should be monitored. Sympathomimetic effects may also modestly alter glucose.
What this interaction means in plain words
Dapagliflozin-metformin and Phentermine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dapagliflozin-metformin belongs to Endocrine; Phentermine belongs to Central Nervous System.
Why it happens
Reduced food intake and weight loss change insulin sensitivity and glycemic needs.
What to do
Monitor glucose when starting phentermine and reduce antidiabetic doses if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Other interactions of Phentermine
- Isocarboxazid + Phentermine Contraindicated
- Linezolid + Phentermine Contraindicated
- Phenelzine + Phentermine Contraindicated
- Phentermine + Procarbazine Contraindicated
- Phentermine + Rasagiline Contraindicated
- Phentermine + Selegiline Contraindicated
Frequently asked questions
Can I take Dapagliflozin-metformin with Phentermine?
MediHelp rates the interaction as minor. Dapagliflozin-metformin and Phentermine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Phentermine-related weight loss and reduced intake often lower antidiabetic requirements, so glucose should be monitored. Sympathomimetic effects may also modestly alter glucose.
How serious is the interaction between Dapagliflozin-metformin and Phentermine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when starting phentermine and reduce antidiabetic doses if hypoglycemia occurs.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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