Drug interactions
Dapsone + Famotidine
Severity: Minor
Dapsone and Famotidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dapsone absorption may be reduced at higher gastric pH, though evidence is limited and the effect appears small. Clinical consequences are generally minor.
What this interaction means in plain words
Dapsone and Famotidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dapsone belongs to Anti Bacterial; Famotidine belongs to Gastrointestinal Tract.
Why it happens
Reduced gastric acidity may modestly decrease dapsone dissolution and absorption.
What to do
No routine adjustment is needed; watch for reduced therapeutic response if acid suppression is prolonged.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Famotidine
Other interactions of Dapsone
- Bcg vaccine live + Dapsone Major
- Dapsone + Primaquine Major
- Apalutamide + Dapsone Moderate
- Belzutifan + Dapsone Moderate
- Bosentan + Dapsone Moderate
- Bupivacaine implant + Dapsone Moderate
Frequently asked questions
Can I take Dapsone with Famotidine?
MediHelp rates the interaction as minor. Dapsone and Famotidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dapsone absorption may be reduced at higher gastric pH, though evidence is limited and the effect appears small. Clinical consequences are generally minor.
How serious is the interaction between Dapsone and Famotidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; watch for reduced therapeutic response if acid suppression is prolonged.
What other medicines interact with Famotidine?
MediHelp also lists interactions of Famotidine with, for example, Atazanavir, Dasatinib, Infigratinib. The full list is on the Famotidine page.
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