Drug interactions
Dasatinib + Dutasteride-tamsulosin
Severity: Minor
Dasatinib and Dutasteride-tamsulosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib is a weak to moderate CYP3A4 inhibitor and may raise dutasteride and tamsulosin exposure modestly. Clinical consequences are expected to be small, with possible mild increases in dizziness or hypotension from tamsulosin.
What this interaction means in plain words
Dasatinib and Dutasteride-tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dasatinib belongs to Oncology; Dutasteride-tamsulosin belongs to Genitourinary.
Why it happens
Weak inhibition of CYP3A4-mediated metabolism of dutasteride and tamsulosin by dasatinib.
What to do
No dose change is usually needed; ask patients to report dizziness or lightheadedness on standing and review the tamsulosin dose if orthostatic symptoms appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dutasteride-tamsulosin
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Dutasteride-tamsulosin?
MediHelp rates the interaction as minor. Dasatinib and Dutasteride-tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dasatinib is a weak to moderate CYP3A4 inhibitor and may raise dutasteride and tamsulosin exposure modestly. Clinical consequences are expected to be small, with possible mild increases in dizziness or hypotension from tamsulosin.
How serious is the interaction between Dasatinib and Dutasteride-tamsulosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; ask patients to report dizziness or lightheadedness on standing and review the tamsulosin dose if orthostatic symptoms appear.
What other medicines interact with Dutasteride-tamsulosin?
MediHelp also lists interactions of Dutasteride-tamsulosin with, for example, Alfuzosin, Amifostine, Atazanavir. The full list is on the Dutasteride-tamsulosin page.
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