Drug interactions
Dasatinib + Fluticasone-vilanterol
Severity: Moderate
Dasatinib and Fluticasone-vilanterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib can prolong the QT interval, and vilanterol may add tachycardia and hypokalemia. The combination may increase arrhythmia risk in patients with other risk factors.
What this interaction means in plain words
Dasatinib and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dasatinib belongs to Oncology; Fluticasone-vilanterol belongs to Respiratory.
Why it happens
Additive QT prolongation and beta-2 agonist-related hypokalemia.
What to do
Correct potassium and magnesium before and during therapy. Obtain an ECG at baseline and when symptoms or other QT-prolonging drugs are added.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fluticasone-vilanterol
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Fluticasone-vilanterol?
MediHelp rates the interaction as moderate. Dasatinib and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dasatinib can prolong the QT interval, and vilanterol may add tachycardia and hypokalemia. The combination may increase arrhythmia risk in patients with other risk factors.
How serious is the interaction between Dasatinib and Fluticasone-vilanterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct potassium and magnesium before and during therapy. Obtain an ECG at baseline and when symptoms or other QT-prolonging drugs are added.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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