Drug interactions
Dasatinib + Ipratropium-salbutamol
Severity: Moderate
Dasatinib and Ipratropium-salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib can prolong the QT interval, and high-dose or systemically significant salbutamol can cause tachycardia, hypokalemia and QT prolongation. Combined use may add to the risk of arrhythmia, especially with electrolyte disturbance or heart disease.
What this interaction means in plain words
Dasatinib and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dasatinib belongs to Oncology; Ipratropium-salbutamol belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta-2 agonist-induced hypokalemia further increasing arrhythmic susceptibility.
What to do
Check potassium and magnesium and correct deficits before and during therapy. Obtain an ECG in patients with cardiac risk factors or when salbutamol use is frequent or high-dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Ipratropium-salbutamol?
MediHelp rates the interaction as moderate. Dasatinib and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dasatinib can prolong the QT interval, and high-dose or systemically significant salbutamol can cause tachycardia, hypokalemia and QT prolongation. Combined use may add to the risk of arrhythmia, especially with electrolyte disturbance or heart disease.
How serious is the interaction between Dasatinib and Ipratropium-salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and correct deficits before and during therapy. Obtain an ECG in patients with cardiac risk factors or when salbutamol use is frequent or high-dose.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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