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Drug interactions

Deferasirox + Maraviroc

Severity: Minor

Deferasirox and Maraviroc: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Deferasirox may reduce maraviroc concentrations through CYP3A4 induction. Lower maraviroc exposure could reduce antiviral efficacy, although the effect is expected to be small.

What this interaction means in plain words

Deferasirox and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Deferasirox belongs to Miscellaneous; Maraviroc belongs to Anti Virals.

Evidence level: Low

Why it happens

Possible weak CYP3A4 induction by deferasirox increases maraviroc metabolism.

What to do

Monitor viral load and virologic response to maraviroc when starting or stopping deferasirox.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Deferasirox with Maraviroc?

MediHelp rates the interaction as minor. Deferasirox and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may reduce maraviroc concentrations through CYP3A4 induction. Lower maraviroc exposure could reduce antiviral efficacy, although the effect is expected to be small.

How serious is the interaction between Deferasirox and Maraviroc?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor viral load and virologic response to maraviroc when starting or stopping deferasirox.

What other medicines interact with Deferasirox?

MediHelp also lists interactions of Deferasirox with, for example, Acetylsalicylic acid, Alosetron, Aluminum hydroxide. The full list is on the Deferasirox page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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