Drug interactions
Deferasirox + Ubrogepant
Severity: Minor
Deferasirox and Ubrogepant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox has been reported to lower exposure to some CYP3A4 substrates, so ubrogepant levels could fall and its effect on migraine may be reduced. The effect is probably small and is mostly predicted from the mechanism.
What this interaction means in plain words
Deferasirox and Ubrogepant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deferasirox belongs to Miscellaneous; Ubrogepant belongs to Central Nervous System.
Why it happens
Deferasirox may weakly induce CYP3A4, increasing the metabolism of ubrogepant.
What to do
Assess response to ubrogepant. If efficacy is inadequate, a dose increase within labeled limits may be considered.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deferasirox
Other interactions of Ubrogepant
- Clarithromycin + Ubrogepant Contraindicated
- Itraconazole + Ubrogepant Contraindicated
- Ketoconazole + Ubrogepant Contraindicated
- Posaconazole + Ubrogepant Contraindicated
- Ubrogepant + Voriconazole Contraindicated
- Apalutamide + Ubrogepant Major
Frequently asked questions
Can I take Deferasirox with Ubrogepant?
MediHelp rates the interaction as minor. Deferasirox and Ubrogepant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox has been reported to lower exposure to some CYP3A4 substrates, so ubrogepant levels could fall and its effect on migraine may be reduced. The effect is probably small and is mostly predicted from the mechanism.
How serious is the interaction between Deferasirox and Ubrogepant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess response to ubrogepant. If efficacy is inadequate, a dose increase within labeled limits may be considered.
What other medicines interact with Deferasirox?
MediHelp also lists interactions of Deferasirox with, for example, Acetylsalicylic acid, Alosetron, Aluminum hydroxide. The full list is on the Deferasirox page.
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