Drug interactions
Deflazacort + Miglitol
Severity: Moderate
Deflazacort and Miglitol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deflazacort, a glucocorticoid, can raise blood glucose and reduce the effectiveness of antidiabetic drugs such as miglitol. Loss of glycemic control may occur, especially with higher doses or prolonged use.
What this interaction means in plain words
Deflazacort and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Miglitol belongs to Endocrine.
Why it happens
Glucocorticoid-induced insulin resistance and increased hepatic gluconeogenesis oppose the glucose-lowering effect of miglitol.
What to do
Monitor blood glucose, including postprandial values, when starting or adjusting deflazacort and intensify antidiabetic therapy if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Miglitol
- Miglitol + Pramlintide Major
- Aripiprazole + Miglitol Moderate
- Asenapine + Miglitol Moderate
- Chlorthalidone + Miglitol Moderate
- Clozapine + Miglitol Moderate
- Cortisone + Miglitol Moderate
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Miglitol?
MediHelp rates the interaction as moderate. Deflazacort and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deflazacort, a glucocorticoid, can raise blood glucose and reduce the effectiveness of antidiabetic drugs such as miglitol. Loss of glycemic control may occur, especially with higher doses or prolonged use.
How serious is the interaction between Deflazacort and Miglitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose, including postprandial values, when starting or adjusting deflazacort and intensify antidiabetic therapy if needed.
What other medicines interact with Miglitol?
MediHelp also lists interactions of Miglitol with, for example, Pramlintide, Aripiprazole, Asenapine. The full list is on the Miglitol page.
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