Drug interactions
Degarelix + Sevoflurane
Severity: Minor
Degarelix and Sevoflurane: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Degarelix, like other androgen deprivation therapies, may prolong the QT interval and sevoflurane can also affect repolarization. The combined effect is probably small but may matter in patients with other risk factors.
What this interaction means in plain words
Degarelix and Sevoflurane have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Degarelix belongs to Endocrine; Sevoflurane belongs to Central Nervous System.
Why it happens
Possible additive QT prolongation, with the effect of androgen deprivation being indirect.
What to do
No routine change is needed. Check the ECG and electrolytes in patients with other QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sevoflurane
Other interactions of Degarelix
- Degarelix + Pimozide Contraindicated
- Degarelix + Thioridazine Contraindicated
- Amiodarone + Degarelix Major
- Amisulpride + Degarelix Major
- Anagrelide + Degarelix Major
- Cisapride + Degarelix Major
Frequently asked questions
Can I take Degarelix with Sevoflurane?
MediHelp rates the interaction as minor. Degarelix and Sevoflurane have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Degarelix, like other androgen deprivation therapies, may prolong the QT interval and sevoflurane can also affect repolarization. The combined effect is probably small but may matter in patients with other risk factors.
How serious is the interaction between Degarelix and Sevoflurane?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Check the ECG and electrolytes in patients with other QT risk factors.
What other medicines interact with Sevoflurane?
MediHelp also lists interactions of Sevoflurane with, for example, Amiodarone, Amisulpride, Arsenic trioxide. The full list is on the Sevoflurane page.
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