Drug interactions
Desflurane + Nebivolol
Severity: Moderate
Desflurane and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Desflurane causes vasodilation and myocardial depression, which adds to the effects of nebivolol. Hypotension and bradycardia can occur during anesthesia.
What this interaction means in plain words
Desflurane and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desflurane belongs to Central Nervous System; Nebivolol belongs to Cardiovascular.
Why it happens
Additive cardiovascular depression from volatile anesthetic vasodilation and beta-1 blockade.
What to do
Monitor hemodynamics continuously and adjust anesthetic depth. Treat hypotension or bradycardia promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Other interactions of Desflurane
Frequently asked questions
Can I take Desflurane with Nebivolol?
MediHelp rates the interaction as moderate. Desflurane and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Desflurane causes vasodilation and myocardial depression, which adds to the effects of nebivolol. Hypotension and bradycardia can occur during anesthesia.
How serious is the interaction between Desflurane and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemodynamics continuously and adjust anesthetic depth. Treat hypotension or bradycardia promptly.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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