Drug interactions
Desipramine + Ipratropium
Severity: Minor
Desipramine and Ipratropium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Desipramine has anticholinergic activity, although less than some other tricyclics, and ipratropium may add to dry mouth, constipation, urinary retention and blurred vision. The effect is typically modest with standard inhaled ipratropium doses.
What this interaction means in plain words
Desipramine and Ipratropium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Desipramine belongs to Central Nervous System; Ipratropium belongs to Respiratory.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Monitor for anticholinergic symptoms, particularly in elderly patients or those with glaucoma. No dose change is usually required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium
- Aclidinium + Ipratropium Moderate
- Benztropine + Ipratropium Moderate
- Bethanechol + Ipratropium Moderate
- Cevimeline + Ipratropium Moderate
- Chlorpromazine + Ipratropium Moderate
- Clomipramine + Ipratropium Moderate
Other interactions of Desipramine
- Desipramine + Disopyramide Contraindicated
- Desipramine + Dofetilide Contraindicated
- Desipramine + Ibutilide Contraindicated
- Desipramine + Isocarboxazid Contraindicated
- Desipramine + Methylene blue Contraindicated
- Desipramine + Pentamidine Contraindicated
Frequently asked questions
Can I take Desipramine with Ipratropium?
MediHelp rates the interaction as minor. Desipramine and Ipratropium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Desipramine has anticholinergic activity, although less than some other tricyclics, and ipratropium may add to dry mouth, constipation, urinary retention and blurred vision. The effect is typically modest with standard inhaled ipratropium doses.
How serious is the interaction between Desipramine and Ipratropium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic symptoms, particularly in elderly patients or those with glaucoma. No dose change is usually required.
What other medicines interact with Ipratropium?
MediHelp also lists interactions of Ipratropium with, for example, Aclidinium, Benztropine, Bethanechol. The full list is on the Ipratropium page.
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