Drug interactions
Desmopressin + Mometasone
Severity: Minor
Desmopressin and Mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids have been reported to increase the risk of hyponatremia with desmopressin. With inhaled mometasone, systemic exposure is low and the risk is likely small.
What this interaction means in plain words
Desmopressin and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Desmopressin belongs to Endocrine; Mometasone belongs to Respiratory.
Why it happens
Additive effects on water retention and sodium balance; the mechanism with low-dose inhaled corticosteroid is not well established.
What to do
Monitor serum sodium if there are symptoms of hyponatremia or risk factors such as high fluid intake.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mometasone
- Mometasone + Ritonavir Major
- Atazanavir + Mometasone Moderate
- Clarithromycin + Mometasone Moderate
- Cobicistat + Mometasone Moderate
- Darunavir + Mometasone Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Mometasone Moderate
Other interactions of Desmopressin
Frequently asked questions
Can I take Desmopressin with Mometasone?
MediHelp rates the interaction as minor. Desmopressin and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids have been reported to increase the risk of hyponatremia with desmopressin. With inhaled mometasone, systemic exposure is low and the risk is likely small.
How serious is the interaction between Desmopressin and Mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum sodium if there are symptoms of hyponatremia or risk factors such as high fluid intake.
What other medicines interact with Mometasone?
MediHelp also lists interactions of Mometasone with, for example, Ritonavir, Atazanavir, Clarithromycin. The full list is on the Mometasone page.
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