Drug interactions
Devil's claw + Ticlopidine
Severity: Minor
Devil's claw and Ticlopidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw has reported but inconsistent antiplatelet or anticoagulant activity. Combined with ticlopidine, it could theoretically add to bleeding tendency. Clinical evidence is limited.
What this interaction means in plain words
Devil's claw and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; the mechanism of devil's claw is not well established.
What to do
Advise patients to report bruising or bleeding and consider avoiding the herb during ticlopidine therapy, especially before procedures.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ticlopidine
Frequently asked questions
Can I take Devil's claw with Ticlopidine?
MediHelp rates the interaction as minor. Devil's claw and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw has reported but inconsistent antiplatelet or anticoagulant activity. Combined with ticlopidine, it could theoretically add to bleeding tendency. Clinical evidence is limited.
How serious is the interaction between Devil's claw and Ticlopidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report bruising or bleeding and consider avoiding the herb during ticlopidine therapy, especially before procedures.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Abrocitinib, Acetylsalicylic acid. The full list is on the Ticlopidine page.
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