Drug interactions
Dexamethasone-tobramycin + Ubrogepant
Severity: Minor
Dexamethasone-tobramycin and Ubrogepant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexamethasone is a weak CYP3A4 inducer and may lower ubrogepant exposure, which could reduce migraine relief. With ophthalmic use the effect is expected to be negligible. Ubrogepant labeling advises dose adjustment with CYP3A4 inducers.
What this interaction means in plain words
Dexamethasone-tobramycin and Ubrogepant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dexamethasone-tobramycin belongs to Anti Bacterial; Ubrogepant belongs to Central Nervous System.
Why it happens
CYP3A4 induction by dexamethasone increasing ubrogepant metabolism.
What to do
No adjustment is needed with ophthalmic use. With prolonged systemic dexamethasone, monitor for reduced efficacy and consider the labeled dose for weak inducers.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexamethasone-tobramycin
Other interactions of Ubrogepant
- Clarithromycin + Ubrogepant Contraindicated
- Itraconazole + Ubrogepant Contraindicated
- Ketoconazole + Ubrogepant Contraindicated
- Posaconazole + Ubrogepant Contraindicated
- Ubrogepant + Voriconazole Contraindicated
- Apalutamide + Ubrogepant Major
Frequently asked questions
Can I take Dexamethasone-tobramycin with Ubrogepant?
MediHelp rates the interaction as minor. Dexamethasone-tobramycin and Ubrogepant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dexamethasone is a weak CYP3A4 inducer and may lower ubrogepant exposure, which could reduce migraine relief. With ophthalmic use the effect is expected to be negligible. Ubrogepant labeling advises dose adjustment with CYP3A4 inducers.
How serious is the interaction between Dexamethasone-tobramycin and Ubrogepant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is needed with ophthalmic use. With prolonged systemic dexamethasone, monitor for reduced efficacy and consider the labeled dose for weak inducers.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
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