Drug interactions
Dexamethasone-tobramycin + Vildagliptin
Severity: Minor
Dexamethasone-tobramycin and Vildagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids raise blood glucose and can reduce the glycemic benefit of vildagliptin. The effect is mainly relevant with systemic or prolonged dexamethasone use.
What this interaction means in plain words
Dexamethasone-tobramycin and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dexamethasone-tobramycin belongs to Anti Bacterial; Vildagliptin belongs to Endocrine.
Why it happens
Glucocorticoid-induced insulin resistance and gluconeogenesis oppose the effect of the DPP-4 inhibitor.
What to do
Monitor blood glucose during steroid therapy and adjust antidiabetic treatment if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexamethasone-tobramycin
Other interactions of Vildagliptin
- Ciprofloxacin + Vildagliptin Moderate
- Deflazacort + Vildagliptin Moderate
- Dexamethasone + Vildagliptin Moderate
- Gemifloxacin + Vildagliptin Moderate
- Glimepiride + Vildagliptin Moderate
- Hydrochlorothiazide-lisinopril + Vildagliptin Moderate
Frequently asked questions
Can I take Dexamethasone-tobramycin with Vildagliptin?
MediHelp rates the interaction as minor. Dexamethasone-tobramycin and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids raise blood glucose and can reduce the glycemic benefit of vildagliptin. The effect is mainly relevant with systemic or prolonged dexamethasone use.
How serious is the interaction between Dexamethasone-tobramycin and Vildagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during steroid therapy and adjust antidiabetic treatment if needed.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
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