Drug interactions
Dexbrompheniramine + Levetiracetam
Severity: Moderate
Dexbrompheniramine and Levetiracetam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause drowsiness and impaired concentration. Taken together, sedation and psychomotor impairment may be greater than with either drug alone, which affects driving and other safety-sensitive tasks.
What this interaction means in plain words
Dexbrompheniramine and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dexbrompheniramine belongs to Respiratory; Levetiracetam belongs to Central Nervous System.
Why it happens
Additive central nervous system depression from the sedating antihistamine and the antiepileptic.
What to do
Warn the patient about additive drowsiness and advise against driving until the response is known. Consider a non-sedating antihistamine if sedation becomes troublesome.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levetiracetam
Other interactions of Dexbrompheniramine
- Amisulpride + Dexbrompheniramine Moderate
- Asenapine + Dexbrompheniramine Moderate
- Brexpiprazole + Dexbrompheniramine Moderate
- Brimonidine + Dexbrompheniramine Moderate
- Brivaracetam + Dexbrompheniramine Moderate
- Cariprazine + Dexbrompheniramine Moderate
Frequently asked questions
Can I take Dexbrompheniramine with Levetiracetam?
MediHelp rates the interaction as moderate. Dexbrompheniramine and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause drowsiness and impaired concentration. Taken together, sedation and psychomotor impairment may be greater than with either drug alone, which affects driving and other safety-sensitive tasks.
How serious is the interaction between Dexbrompheniramine and Levetiracetam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn the patient about additive drowsiness and advise against driving until the response is known. Consider a non-sedating antihistamine if sedation becomes troublesome.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
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