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Drug interactions

Dexlansoprazole + Eslicarbazepine

Severity: Minor

Dexlansoprazole and Eslicarbazepine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Eslicarbazepine inhibits CYP2C19, which may modestly raise dexlansoprazole exposure. The clinical effect is expected to be small given the PPI's wide margin.

What this interaction means in plain words

Dexlansoprazole and Eslicarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Dexlansoprazole belongs to Gastrointestinal Tract; Eslicarbazepine belongs to Central Nervous System.

Evidence level: Low

Why it happens

Eslicarbazepine inhibits CYP2C19, reducing dexlansoprazole metabolism.

What to do

No dose adjustment is usually needed; monitor for PPI adverse effects with long-term use.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dexlansoprazole with Eslicarbazepine?

MediHelp rates the interaction as minor. Dexlansoprazole and Eslicarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eslicarbazepine inhibits CYP2C19, which may modestly raise dexlansoprazole exposure. The clinical effect is expected to be small given the PPI's wide margin.

How serious is the interaction between Dexlansoprazole and Eslicarbazepine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed; monitor for PPI adverse effects with long-term use.

What other medicines interact with Dexlansoprazole?

MediHelp also lists interactions of Dexlansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Dexlansoprazole page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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