Drug interactions
Diazepam + Fenfluramine
Severity: Minor
Diazepam and Fenfluramine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenfluramine is used in seizure disorders and may be combined with benzodiazepines such as diazepam. Fenfluramine itself can cause somnolence and the effect of the combination on sedation is not clearly established.
What this interaction means in plain words
Diazepam and Fenfluramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Diazepam belongs to Musculoskeletal; Fenfluramine belongs to Central Nervous System.
Why it happens
No established mechanism; possible additive or opposing CNS effects.
What to do
Monitor sedation and seizure control when combining and adjust doses according to response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Diazepam
Other interactions of Fenfluramine
- Fenfluramine + Isocarboxazid Contraindicated
- Fenfluramine + Linezolid Contraindicated
- Fenfluramine + Phenelzine Contraindicated
- Fenfluramine + Selegiline Contraindicated
- Fenfluramine + Tranylcypromine Contraindicated
- Almotriptan + Fenfluramine Major
Frequently asked questions
Can I take Diazepam with Fenfluramine?
MediHelp rates the interaction as minor. Diazepam and Fenfluramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fenfluramine is used in seizure disorders and may be combined with benzodiazepines such as diazepam. Fenfluramine itself can cause somnolence and the effect of the combination on sedation is not clearly established.
How serious is the interaction between Diazepam and Fenfluramine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation and seizure control when combining and adjust doses according to response.
What other medicines interact with Diazepam?
MediHelp also lists interactions of Diazepam with, for example, Calcium / magnesium / potassium / sodium oxybates, Alfentanil, Alprazolam. The full list is on the Diazepam page.
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