Drug interactions
Didanosine + Ferric maltol
Severity: Minor
Didanosine and Ferric maltol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Buffered didanosine formulations raise gastric pH and may reduce absorption of oral iron preparations. Ferric maltol is less dependent on acid than iron salts, so the effect is likely small, but iron may also reduce didanosine absorption.
What this interaction means in plain words
Didanosine and Ferric maltol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Didanosine belongs to Anti Virals; Ferric maltol belongs to Miscellaneous.
Why it happens
Raised gastric pH and possible cation chelation may reduce oral iron absorption.
What to do
Separate ferric maltol from buffered didanosine by at least 2 hours. Monitor iron indices if anemia persists.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Didanosine
- Didanosine + Elvitegravir / cobicistat / emtricitabine / tenofovir df Contraindicated
- Didanosine + Hydroxycarbamide Contraindicated
- Didanosine + Ribavirin Contraindicated
- Didanosine + Stavudine Contraindicated
- Allopurinol + Didanosine Major
- Atidarsagene autotemcel + Didanosine Major
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Frequently asked questions
Can I take Didanosine with Ferric maltol?
MediHelp rates the interaction as minor. Didanosine and Ferric maltol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Buffered didanosine formulations raise gastric pH and may reduce absorption of oral iron preparations. Ferric maltol is less dependent on acid than iron salts, so the effect is likely small, but iron may also reduce didanosine absorption.
How serious is the interaction between Didanosine and Ferric maltol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate ferric maltol from buffered didanosine by at least 2 hours. Monitor iron indices if anemia persists.
What other medicines interact with Didanosine?
MediHelp also lists interactions of Didanosine with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Hydroxycarbamide, Ribavirin. The full list is on the Didanosine page.
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