Drug interactions
Dipyridamole + Ozanimod
Severity: Moderate
Dipyridamole and Ozanimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole inhibits BCRP and may increase exposure to ozanimod's active metabolites. This could increase ozanimod adverse effects such as bradycardia, hepatic enzyme elevation and infections.
What this interaction means in plain words
Dipyridamole and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dipyridamole belongs to Cardiovascular; Ozanimod belongs to Central Nervous System.
Why it happens
Dipyridamole inhibits BCRP, potentially reducing efflux of ozanimod and its active metabolites.
What to do
Monitor heart rate and liver enzymes, and consider an alternative to dipyridamole if the interaction is clinically significant.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Dipyridamole with Ozanimod?
MediHelp rates the interaction as moderate. Dipyridamole and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dipyridamole inhibits BCRP and may increase exposure to ozanimod's active metabolites. This could increase ozanimod adverse effects such as bradycardia, hepatic enzyme elevation and infections.
How serious is the interaction between Dipyridamole and Ozanimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and liver enzymes, and consider an alternative to dipyridamole if the interaction is clinically significant.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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