Drug interactions
Dipyridamole + Stiripentol
Severity: Minor
Dipyridamole and Stiripentol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Stiripentol inhibits BCRP in vitro, which may raise exposure to BCRP substrates such as dipyridamole. The clinical effect is probably small and mainly increased vasodilatory adverse effects.
What this interaction means in plain words
Dipyridamole and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Stiripentol belongs to Central Nervous System.
Why it happens
BCRP inhibition by stiripentol, increasing substrate exposure.
What to do
Monitor blood pressure and tolerability. Reduce the dipyridamole dose if adverse effects occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Stiripentol
Frequently asked questions
Can I take Dipyridamole with Stiripentol?
MediHelp rates the interaction as minor. Dipyridamole and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Stiripentol inhibits BCRP in vitro, which may raise exposure to BCRP substrates such as dipyridamole. The clinical effect is probably small and mainly increased vasodilatory adverse effects.
How serious is the interaction between Dipyridamole and Stiripentol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and tolerability. Reduce the dipyridamole dose if adverse effects occur.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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