Drug interactions
Dipyridamole + Vadadustat
Severity: Minor
Dipyridamole and Vadadustat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vadadustat inhibits BCRP and may increase exposure to BCRP substrates such as dipyridamole. Increased dipyridamole effects such as hypotension and headache are possible. The interaction is predicted from transporter data.
What this interaction means in plain words
Dipyridamole and Vadadustat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Vadadustat belongs to Endocrine.
Why it happens
Vadadustat inhibits BCRP-mediated efflux, potentially raising dipyridamole exposure.
What to do
Monitor for dipyridamole adverse effects and reduce its dose if they occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Vadadustat
- Atorvastatin + Vadadustat Moderate
- Balsalazide + Vadadustat Moderate
- Baricitinib + Vadadustat Moderate
- Benzathine penicillin g + Vadadustat Moderate
- Calcium carbonate + Vadadustat Moderate
- Calcium + Vadadustat Moderate
Frequently asked questions
Can I take Dipyridamole with Vadadustat?
MediHelp rates the interaction as minor. Dipyridamole and Vadadustat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vadadustat inhibits BCRP and may increase exposure to BCRP substrates such as dipyridamole. Increased dipyridamole effects such as hypotension and headache are possible. The interaction is predicted from transporter data.
How serious is the interaction between Dipyridamole and Vadadustat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for dipyridamole adverse effects and reduce its dose if they occur.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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