Drug interactions
Dopamine + Fluticasone-salmeterol
Severity: Moderate
Dopamine and Fluticasone-salmeterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dopamine stimulates adrenergic receptors, and salmeterol adds beta-2 agonism, so the combination may increase heart rate, arrhythmia risk and blood pressure variability. Hypokalemia from salmeterol can add to the arrhythmic risk.
What this interaction means in plain words
Dopamine and Fluticasone-salmeterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dopamine belongs to Cardiovascular; Fluticasone-salmeterol belongs to Respiratory.
Why it happens
Additive adrenergic stimulation from dopamine and the beta-2 agonist salmeterol.
What to do
Monitor ECG, heart rate, blood pressure and potassium during dopamine infusion and adjust therapy if tachyarrhythmia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fluticasone-salmeterol
- Darunavir + Fluticasone-salmeterol Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Fluticasone-salmeterol Contraindicated
- Fluticasone-salmeterol + Fosamprenavir Contraindicated
- Fluticasone-salmeterol + Indinavir Contraindicated
- Fluticasone-salmeterol + Lopinavir Contraindicated
- Fluticasone-salmeterol + Nelfinavir Contraindicated
Other interactions of Dopamine
- Dihydroergotamine intranasal + Dopamine Contraindicated
- Dihydroergotamine + Dopamine Contraindicated
- Dopamine + Promethazine Contraindicated
- Dopamine + Selegiline transdermal Contraindicated
- Amitriptyline + Dopamine Major
- Clomipramine + Dopamine Major
Frequently asked questions
Can I take Dopamine with Fluticasone-salmeterol?
MediHelp rates the interaction as moderate. Dopamine and Fluticasone-salmeterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dopamine stimulates adrenergic receptors, and salmeterol adds beta-2 agonism, so the combination may increase heart rate, arrhythmia risk and blood pressure variability. Hypokalemia from salmeterol can add to the arrhythmic risk.
How serious is the interaction between Dopamine and Fluticasone-salmeterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate, blood pressure and potassium during dopamine infusion and adjust therapy if tachyarrhythmia develops.
What other medicines interact with Fluticasone-salmeterol?
MediHelp also lists interactions of Fluticasone-salmeterol with, for example, Darunavir, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Fosamprenavir. The full list is on the Fluticasone-salmeterol page.
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