Drug interactions
Dopamine + Salmeterol
Severity: Moderate
Dopamine and Salmeterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have adrenergic activity, so combined use can increase heart rate and blood pressure and provoke tachyarrhythmias. Beta-2 effects may also lower serum potassium.
What this interaction means in plain words
Dopamine and Salmeterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dopamine belongs to Cardiovascular; Salmeterol belongs to Respiratory.
Why it happens
Additive adrenergic stimulation of cardiovascular beta receptors.
What to do
Monitor ECG, blood pressure and potassium during dopamine infusion in patients on salmeterol. Adjust the dopamine rate for arrhythmia or excessive tachycardia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salmeterol
- Ritonavir + Salmeterol Contraindicated
- Salmeterol + Saquinavir Contraindicated
- Amitriptyline + Salmeterol Major
- Arformoterol + Salmeterol Major
- Atazanavir + Salmeterol Major
- Budesonide-formoterol + Salmeterol Major
Other interactions of Dopamine
- Dihydroergotamine intranasal + Dopamine Contraindicated
- Dihydroergotamine + Dopamine Contraindicated
- Dopamine + Promethazine Contraindicated
- Dopamine + Selegiline transdermal Contraindicated
- Amitriptyline + Dopamine Major
- Clomipramine + Dopamine Major
Frequently asked questions
Can I take Dopamine with Salmeterol?
MediHelp rates the interaction as moderate. Dopamine and Salmeterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have adrenergic activity, so combined use can increase heart rate and blood pressure and provoke tachyarrhythmias. Beta-2 effects may also lower serum potassium.
How serious is the interaction between Dopamine and Salmeterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, blood pressure and potassium during dopamine infusion in patients on salmeterol. Adjust the dopamine rate for arrhythmia or excessive tachycardia.
What other medicines interact with Salmeterol?
MediHelp also lists interactions of Salmeterol with, for example, Ritonavir, Saquinavir, Amitriptyline. The full list is on the Salmeterol page.
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