Drug interactions
Doxazosin + Maraviroc
Severity: Moderate
Doxazosin and Maraviroc: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, particularly in patients with renal impairment or on other blood-pressure-lowering drugs. Combined with doxazosin, orthostatic effects may be additive.
What this interaction means in plain words
Doxazosin and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxazosin belongs to Genitourinary; Maraviroc belongs to Anti Virals.
Why it happens
Additive postural hypotensive effects; maraviroc's mechanism for hypotension is not fully established.
What to do
Counsel patients to rise slowly and check orthostatic blood pressure after starting. Reduce doxazosin if symptomatic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Doxazosin
- Alfuzosin + Doxazosin Major
- Amifostine + Doxazosin Major
- Avanafil + Doxazosin Major
- Doxazosin + Dutasteride-tamsulosin Major
- Doxazosin + Phentolamine Major
- Doxazosin + Prazosin Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Doxazosin with Maraviroc?
MediHelp rates the interaction as moderate. Doxazosin and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension, particularly in patients with renal impairment or on other blood-pressure-lowering drugs. Combined with doxazosin, orthostatic effects may be additive.
How serious is the interaction between Doxazosin and Maraviroc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to rise slowly and check orthostatic blood pressure after starting. Reduce doxazosin if symptomatic.
What other medicines interact with Doxazosin?
MediHelp also lists interactions of Doxazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Doxazosin page.
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