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Drug interactions

Doxercalciferol + Magnesium sulphate

Severity: Minor

Doxercalciferol and Magnesium sulphate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Active vitamin D analogues enhance intestinal magnesium absorption, which may raise serum magnesium. This is relevant mainly in patients with renal impairment who take magnesium-containing products orally.

What this interaction means in plain words

Doxercalciferol and Magnesium sulphate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Vitamin D analogues increase gastrointestinal absorption of magnesium.

What to do

Monitor serum magnesium in patients with chronic kidney disease taking oral magnesium and doxercalciferol.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Doxercalciferol with Magnesium sulphate?

MediHelp rates the interaction as minor. Doxercalciferol and Magnesium sulphate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Active vitamin D analogues enhance intestinal magnesium absorption, which may raise serum magnesium. This is relevant mainly in patients with renal impairment who take magnesium-containing products orally.

How serious is the interaction between Doxercalciferol and Magnesium sulphate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium in patients with chronic kidney disease taking oral magnesium and doxercalciferol.

What other medicines interact with Magnesium sulphate?

MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.

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