Drug interactions
Dutasteride-tamsulosin + Iloprost
Severity: Moderate
Dutasteride-tamsulosin and Iloprost: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a potent vasodilator that can cause hypotension, particularly when given intravenously. Tamsulosin may add to this effect and produce dizziness or syncope.
What this interaction means in plain words
Dutasteride-tamsulosin and Iloprost can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dutasteride-tamsulosin belongs to Genitourinary; Iloprost belongs to Cardiovascular.
Why it happens
Additive vasodilation from prostacyclin receptor agonism and alpha-1 blockade.
What to do
Monitor blood pressure during iloprost initiation and titration. Consider temporarily holding tamsulosin, or reduce the iloprost dose, if hypotension persists.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dutasteride-tamsulosin
Other interactions of Iloprost
- Aldesleukin + Iloprost Moderate
- Amiodarone + Iloprost Moderate
- Bortezomib + Iloprost Moderate
- Bromocriptine + Iloprost Moderate
- Bupivacaine + Iloprost Moderate
- Carbidopa-entacapone-levodopa + Iloprost Moderate
Frequently asked questions
Can I take Dutasteride-tamsulosin with Iloprost?
MediHelp rates the interaction as moderate. Dutasteride-tamsulosin and Iloprost can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloprost is a potent vasodilator that can cause hypotension, particularly when given intravenously. Tamsulosin may add to this effect and produce dizziness or syncope.
How serious is the interaction between Dutasteride-tamsulosin and Iloprost?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during iloprost initiation and titration. Consider temporarily holding tamsulosin, or reduce the iloprost dose, if hypotension persists.
What other medicines interact with Dutasteride-tamsulosin?
MediHelp also lists interactions of Dutasteride-tamsulosin with, for example, Alfuzosin, Amifostine, Atazanavir. The full list is on the Dutasteride-tamsulosin page.
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