Drug interactions
Elagolix + Escitalopram
Severity: Minor
Elagolix and Escitalopram: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix weakly inhibits CYP2C19 and induces CYP3A4, so effects on escitalopram exposure are mixed and probably small. Clinically meaningful changes are not expected in most patients.
What this interaction means in plain words
Elagolix and Escitalopram have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elagolix belongs to Musculoskeletal; Escitalopram belongs to Central Nervous System.
Why it happens
Opposing weak CYP2C19 inhibition and CYP3A4 induction by elagolix altering escitalopram metabolism.
What to do
No routine dose change is needed. Monitor for changes in antidepressant response or adverse effects if symptoms change.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Elagolix with Escitalopram?
MediHelp rates the interaction as minor. Elagolix and Escitalopram have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix weakly inhibits CYP2C19 and induces CYP3A4, so effects on escitalopram exposure are mixed and probably small. Clinically meaningful changes are not expected in most patients.
How serious is the interaction between Elagolix and Escitalopram?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed. Monitor for changes in antidepressant response or adverse effects if symptoms change.
What other medicines interact with Escitalopram?
MediHelp also lists interactions of Escitalopram with, for example, Cisapride, Citalopram, Isocarboxazid. The full list is on the Escitalopram page.
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