Drug interactions
Elagolix + Etoposide
Severity: Minor
Elagolix and Etoposide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak-to-moderate CYP3A4 inducer and may modestly reduce etoposide exposure. The clinical effect is probably small and the combination is uncommon.
What this interaction means in plain words
Elagolix and Etoposide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elagolix belongs to Musculoskeletal; Etoposide belongs to Oncology.
Why it happens
Elagolix induces CYP3A4, increasing etoposide metabolism.
What to do
Monitor clinical response to etoposide. No routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Etoposide
- Adenovirus types 4 and 7 live + Etoposide Contraindicated
- Etoposide + Pentostatin Contraindicated
- Cyclosporine + Etoposide Major
- Cyclosporin + Etoposide Major
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Etoposide Major
- Etoposide + Fingolimod Major
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Elagolix with Etoposide?
MediHelp rates the interaction as minor. Elagolix and Etoposide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak-to-moderate CYP3A4 inducer and may modestly reduce etoposide exposure. The clinical effect is probably small and the combination is uncommon.
How serious is the interaction between Elagolix and Etoposide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to etoposide. No routine dose change is needed.
What other medicines interact with Etoposide?
MediHelp also lists interactions of Etoposide with, for example, Adenovirus types 4 and 7 live, Pentostatin, Cyclosporine. The full list is on the Etoposide page.
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